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10 Enzyme Technology for the Degradation of Lignocellulosic Waste
sulfuric acid, hydrochloric acid, trifluro acetic acid, phosphoric acid, and nitric acid.
Disruption of hemicellulose microfibrils occurs in steam-explosion pre-treatment
[30]. The wastes are subjected to high pressures and temperatures for a short time
followed by depressurization of the system. Sometimes, acid catalysts are used
to aid the steam-explosion system. Wet oxidation and steam explosion combined
together help in the processing large amounts of biomass [31].
10.2.3
Degradation of Lignin
Lignin is a phenolic polymer and is found in every terrestrial plant. Lignins are
derived from 3-hydroxyl-cinnamyl alcohols or monolignols namely, p-coumaryl
alcohol, coniferyl alcohol, and sinapyl alcohol. The monolignols form the building
blocks of lignin. Two monolignol radicals dimerize to form a starting dimeric unit.
It then undergoes cross-coupling with another monolignol/dimeric radical, and
thereby polymerization sets in to biosynthesize lignin. Substituted phenylpropanoid
building units connected to each other by carbon–carbon linkages forming the
backbone of lignin. A precise and simplified definition for lignin is lacking because
of its structure, non-repetitive multi-units, diversity in composition depending on
origins, etc. [32].
10.2.3.1
Microbial Production of Lignin Degrading Enzymes
Due to the diversity in the interunits of lignin, it is not easy to break the internal
bonds. Only a few microorganisms are able to degrade lignins. White-rot basidio-
mycetes, actinomycetes, Phanerochaete chrysosporium, Trichoderma, Streptomyces
cinnamomensis, Lentinus squarrosulus, Schizophyllum commune, Bjerkandera
adusta, Xanthomonas sp., Fomitopsis palustris, and Aspergillus are able to efficiently
degrade lignin.
Phanerochaete chrysosporium is extensively studied in lignin degradation and also
been commercially used for lignocellulosic waste degradation. It produces 10 lignin
peroxidases (LiP), 5 manganese peroxidases (MnP), and several other lignocellu-
lolytic enzymes [33]. Another phytopathogenic fungus, Chondrostereum purpureum
also produces many lignocellulolytic enzymes [34].
10.2.3.2
Enzymes Responsible for the Degradation of Lignin
Lignin degradation is a difficult task to achieve by microorganisms. There are many
complexities in the lignin structure. First, lignin is a large polymer, and hence,
the enzymes required should be extracellular. Second, since the interunit bonds
are carbon–carbon and ether bonds, oxidative degradation rather than hydrolytic
breakdown is essential. And third, owing to its irregular structure, the enzymes
needed should be less specific in nature [35]. The enzymes utilized for lignin
degradation are known as ligninases or lignin-modifying enzymes. Ligninases
are grouped into two classes viz., heme peroxidases and phenol oxidases. LiP,
MnP, versatile peroxidases (VP), and dye decolorizing peroxidases come under the